RELATIONSHIP BETWEEN ANASTOMOTIC STRICTURE AND TYPE OF SUTURE AFTER RADICAL PROSTATECTOMY

==inizio abstract==

Objectives:
stricture of the vesicourethral anastomosis remains a well-documented complication after radical prostatectomy, it’s occurs in 0,5 to 32% of man after radical prostatectomy. We evaluate the relationship between anastomotic stricture and type of suture.

Methods:
from 2008 al 2011 we looked incidence of anastomotic strictures in 210 patients randomized in two groups: in 110 patients we performed vesicourethral interrupted anastomosis with 3-0 absorbable braided suture (group A), in 100 patients with 3-0 absorbable monofilament suture (group B).
Al patients performed neck sparing radical prostatectomy.

Results:
There were no significant differences in two groups, in age, Gleason score, nerve-sparing status, intraoperative blood loss, degree of extravasation on initial cystography, or duration of the indwelling urinary catheter. While 9 patients (8,1%) developed an anastomotic stricture in group A, but no one in group B developed a stricture (P< 0,01). In 6 patients (56%), the bladder neck stricture occurred within 3 months after surgery, in 3 (28%) at 4-12 months after surgery and in nobody more than 12 months after surgery. Probably absorbable braided suture could be induce a flogistic reaction and conseguentely an anastomotic stricture. Conclusions: From 2012 we performed vesicourethral interrupted anastomosis with 3-0 absorbable monofilament suture in all patients and no one developed a stricture. In our experiences the type of suture is significant parameter for the anastomotic stricture. ==fine abstract==